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  • Title: Susceptibility of Schistosoma mansoni prevalent in Saudi Arabia to oxamniquine in experimentally infected mice.
    Author: Amin AM, Mikhail EG.
    Journal: J Trop Med Hyg; 1988 Aug; 91(4):192-5. PubMed ID: 3136251.
    Abstract:
    The therapeutic efficiency of oxamniquine against the local strain of Schistosoma mansoni was investigated in experimentally infected mice. The drug was administered orally using a human-equivalent dose of 20 mg kg-1 day-1 for 3 consecutive days (total dose of 60 mg kg-1). Oxamniquine proved to be very effective as indicated by hepatic shift, oogram changes, complete elimination of adult worms and eradication of faecal eggs.
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