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  • Title: [Post-antibiotic effect of ciprofloxacin alone and in combination on Streptococcus faecalis].
    Author: Zuccarelli M, Simeon de Buochberg M, Maillols H, Dusart G, Attisso MA.
    Journal: Pathol Biol (Paris); 1988 May; 36(5):410-3. PubMed ID: 3136423.
    Abstract:
    Post-antibiotic effect (PAE) of ciprofloxacin has been studied on 2 strains of S. faecalis in the logarithmic phase after 2 exposure times and at concentrations ranging 0.5-10 times the MIC. At the end of the exposure period the antimicrobial is removed by dilution. Similar PAE is observed for ciprofloxacin and ofloxacin, higher than for pefloxacin. Ciprofloxacin-fosfomycin or ciprofloxacin-vancomycin combinations are indifferent or even antagonistic (vancomycin) in regards to PAE. Ciprofloxacin-penicillin or ciprofloxacin-netilmicin are weakly synergistic.
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