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  • Title: Rh disease: intravascular fetal blood transfusion by cordocentesis.
    Author: Nicolaides KH, Soothill PW, Rodeck CH, Clewell W.
    Journal: Fetal Ther; 1986; 1(4):185-92. PubMed ID: 3136620.
    Abstract:
    A total of 130 cordocenteses, including 96 intravascular fetal blood transfusions, were performed in 21 pregnancies complicated by red cell isoimmunization. Transfusions were commended at 18-34 weeks' gestation and repeated up to 7 times, at 1- to 4-week intervals. The volumes of transfused blood were 5-150 ml, the haematocrits 62-88% and the rate of transfusions 1-15 ml/min. The pretransfusion fetal haematocrits were 5-34% and the posttransfusion ones 28-60%. Final transfusions were given at 32-36 weeks' gestation. Of the 21 pregnancies, 18 delivered at 31-39 weeks and 3 are continuing; 1 baby was stillborn and 17 are alive and well.
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