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  • Title: Studies of neurocirculatory effects of long-term L-threo-3,4-dihydroxyphenylserine administration in a patient with familial amyloidotic polyneuropathy.
    Author: Azuma T, Suzuki T, Mizuno R, Tsujino S, Kishimoto S, Mizuta E, Ichikawa K.
    Journal: Acta Neurol Scand; 1988 May; 77(5):409-13. PubMed ID: 3137768.
    Abstract:
    The case is reported of a 57-year-old woman with familial amyloidotic polyneuropathy and concomitant orthostatic hypotension for which L-threo-3,4-dihydroxyphenylserine (L-threo-DOPS) was clinically effective. Testing of autonomic function under telemetric intra-arterial pressure monitoring before and during L-threo-DOPS treatment clearly demonstrated the pathophysiology of the sympathetic nervous system and its modification by L-threo-DOPS.
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