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  • Title: Synthesis and bioactivity of indoleacetic acid-carbendazim and its effects on Cylindrocladium parasiticum.
    Author: Yang J, Ye T, Liu G, Xu X, Zheng Y, Wang W.
    Journal: Pestic Biochem Physiol; 2019 Jul; 158():128-134. PubMed ID: 31378348.
    Abstract:
    Indoleacetic acid (IAA)-carbendazim was synthesized to assess whether this conjugate could retain the fungicidal activity of carbendazim and gain root-inducing properties upon the addition of an indoleacetic acid group. An indoor virulence test demonstrated that the conjugate retained the fungicidal activity of carbendazim towards Cylindrocladium parasiticum. The conjugate was detected in roots after soaking Ricinus communis L. leaves into a solution of the IAA-carbendazim, which confirmed its phloem mobility. The activities of the cellulase, polygalacturonase and xylanase produced by Cylindrocladium parasiticum treated with different concentrations of the conjugate were determined, and the peak activities appeared at 72 h or 96 h. More importantly, the conjugate showed the ability to promote root growth. These results revealed that indoleacetic acid-carbendazim may be useful in preventing Cylindrocladium parasiticum and other diseases.
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