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  • Title: Blue emitting nitrogen-doped carbon dots as a fluorescent probe for nitrite ion sensing and cell-imaging.
    Author: Jana J, Lee HJ, Chung JS, Kim MH, Hur SH.
    Journal: Anal Chim Acta; 2019 Nov 04; 1079():212-219. PubMed ID: 31387714.
    Abstract:
    This study examined the efficiency of pH-dependent, fluorescent carbon dots for the sensing of hazardous anions in aqueous media and cell imaging. The nitrite anion, an important water-soluble element for environmental and biological systems, requires continuous monitoring because a high concentration can affect the systems severely. The as-synthesized carbon dots efficiently detected the nitrite anion in aqueous solution through a fluorescent 'Turn Off' phenomenon. The quenching mechanism was investigated through proper microscopic and spectroscopic studies. The limit of detection and linear detection range were 7.9 nM and 2.3μM-7.7 mM, respectively. The sensitivity was tested with different water samples. In a parallel experiment, the as-synthesized carbon dots were used as a cell-imaging probe for HeLa cells, highlighting their potential in different biological studies.
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