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Title: Bone marrow transplantation from an unrelated donor for Fanconi's anaemia: two unusual complications. Author: Sokal E, Michel M, Ninane J, Latinne D, de Bruyere M, Cornu G. Journal: Bone Marrow Transplant; 1987 Jun; 2(1):99-102. PubMed ID: 3139115. Abstract: An eight-year-old boy with Fanconi's anaemia received a bone marrow transplantation from an unrelated donor. Sustained engraftment was achieved, but he developed major complications including acute grade III graft-versus-host disease, autoimmune haemolytic anaemia with positive Coombs' test and free antibodies against Rhesus group, and a virus-associated haemophagocytic syndrome; this latter complication was successfully treated with acyclovir. Sixteen months after transplantation he has full haematopoietic reconstitution, but with persisting mild autoimmune haemolysis.[Abstract] [Full Text] [Related] [New Search]