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  • Title: Belimumab treatment in rhupus: A case report with severe skin involvement.
    Author: Castillo Dayer PV, Lozano Rivas N, Martínez Ferrín JJ, Victoria Martínez AM, Sánchez-Pedreño Guillen P, Marras Fernández-Cid C.
    Journal: Dermatol Ther; 2019 Sep; 32(5):e13056. PubMed ID: 31393634.
    Abstract:
    Patients with rhupus characteristically exhibit symmetric polyarthritis and clinical manifestations suggestive of systemic lupus erythematosus (malar rash, photosensitivity, hematological manifestations, serositis, and/or skin involvement) and positive anti-dsDNA. Treatment is unclear and it can include disease-modifying rheumatic drugs like hydroxyl chloroquine, or methotrexate or, in refractory cases, rituximab or abatacept. We report a case of 31-year-old female who present with rhupus with skin acute lesions treated with belimumab. This is the first case of rhupus treated with this drug described in the literature.
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