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  • Title: [D-penicillamin-induced IgA-deficiency (author's transl)].
    Author: Götze H.
    Journal: Klin Padiatr; 1979 Jul; 191(4):433-5. PubMed ID: 314018.
    Abstract:
    A 6 year old girl developed IgA-deficiency following treatment for chronic hepatitis with D-penicillamine. 4 months after discontinuation of the drug serum IgA and the number of circulating B-lymphocytes were still markedly reduced, in addition secretory IgA was diminished relative to secretory IgM. D-penicillamine should be used only if absolutely necessary and during treatment frequent monitoring of immunoglobulin levels becomes mandatory.
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