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  • Title: [Long-term chemotherapy in patients with stage IV gastric cancer after surgical treatment--a randomized comparative study of FT-207 and UFT].
    Author: Sugimachi K, Okamura T, Furusawa M, Saku M, Noda S, Matsusaka T, Teraoka H, Toda T, Oka N, Inokuchi K.
    Journal: Gan To Kagaku Ryoho; 1988 Oct; 15(10):2953-7. PubMed ID: 3140734.
    Abstract:
    A prospective randomized and comparative study of FT-207 and UFT was performed for cases of Stage IV gastric cancer involving long-term cancer chemotherapy after surgery. Immediately after the surgery, the subjects were randomly divided into two groups: A group treated by MMC and FT-207: and B group treated by MMC and UFT. From a total of 54 cases, 8 cases were excluded, so that A group consisted of 24 subjects and B group of 22 subjects. There were no differences in background factors between the two groups. In a comparison of all the cases, B group revealed a significantly higher survival rate than A group. These results indicated that the simultaneous use of MMC and UFT was effective as a long-term cancer chemotherapy after surgery for patients with Stage IV gastric cancer.
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