These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Nanoparticle-Biofilm Interactions: The Role of the EPS Matrix.
    Author: Fulaz S, Vitale S, Quinn L, Casey E.
    Journal: Trends Microbiol; 2019 Nov; 27(11):915-926. PubMed ID: 31420126.
    Abstract:
    The negative consequences of biofilms are widely reported. A defining feature of biofilms is the extracellular matrix, a complex mixture of biomacromolecules, termed EPS, which contributes to reduced antimicrobial susceptibility. EPS targeting is a promising, but underexploited, approach to biofilm control allowing disruption of the matrix and thereby increasing the susceptibility to antimicrobials. Nanoparticles (NPs) can play a very important role as 'carriers' of EPS matrix disruptors, and several approaches have recently been proposed. In this review, we discuss the application of nanoparticles as antibiofilm technologies with a special emphasis on the role of the EPS matrix in the physicochemical regulation of the nanoparticle-biofilm interaction. We highlight the use of nanoparticles as a platform for a new generation of antibiofilm approaches.
    [Abstract] [Full Text] [Related] [New Search]