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Title: Lymphocyte-associated immune responses to canine distemper and measles viruses in distemper-infected gnotobiotic dogs. Author: Krakowka S, Wallace AL. Journal: Am J Vet Res; 1979 May; 40(5):669-72. PubMed ID: 314249. Abstract: Cellular immune responses of peripheral blood lymphocytes to canine distemper virus and measles virus were determined in vaccinated or infected gnotobiotic dogs, using the technique of syncytia inhibition. Cross-reactivity between viruses was detected in both groups of dogs. Peak responses in vaccinated dogs occurred 11 days after vaccination and declined to base-line levels by 3 weeks, whereas responses in infected dogs were present 30 days after inoculation. Fractionation experiments with peripheral blood lymphocytes indicated that synctia inhibition is probably mediated by T lymphocytes.[Abstract] [Full Text] [Related] [New Search]