These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Clinical and biological survey of haemophilia A and B patients infused with French heat-treated concentrates.
    Author: Parquet A, Boneu B, Bosser C, Cazenave JP, Dirat G, Gazengel G, Grunebaum L, Sultan Y, Verroust F, Wiesel ML.
    Journal: Nouv Rev Fr Hematol (1978); 1988; 30(4):205-7. PubMed ID: 3143099.
    Abstract:
    The efficiency of heat treatment procedures of factor VIII and factor IX concentrates, prepared from voluntary, non-paid donors by three French Blood Transfusion Centres, on the inactivation of HIV and non-A, non-B hepatitis (NANB) viruses was assessed. Some 43 patients (26 haemophilia A, 17 haemophilia B) were followed for at least 1 year by testing for HIV antibodies and alanine aminotransferase (ALT). No HIV seroconversion was observed indicating that heat treatment was completely efficient. Among 26 haemophiliacs, 6 (4 haemophilia A, 2 haemophilia B) presented an elevation in ALT, indicating only a 75% reduction of NANB viral contamination.
    [Abstract] [Full Text] [Related] [New Search]