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  • Title: The effects of phenobarbital on serum high density lipoprotein subfractions and apolipoproteins.
    Author: Luoma PV, Marniemi J, Sotaniemi EA.
    Journal: Res Commun Chem Pathol Pharmacol; 1988 Oct; 62(1):125-8. PubMed ID: 3144720.
    Abstract:
    Prospective studies report that a pharmacologic elevation of serum high density lipoprotein (HDL) concentration may be of value in the prevention of atherosclerosis. In this study phenobarbital, 50 mg at bedtime for ten days, increased serum HDL cholesterol, HDL2 cholesterol and HDL cholesterol/cholesterol and HDL cholesterol/apolipoprotein A-I ratios. Phenobarbital treated subjects had serum lipoprotein profile typical of low risk of ischemic heart disease.
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