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Title: Soy Biodiesel Exhaust is More Toxic than Mineral Diesel Exhaust in Primary Human Airway Epithelial Cells. Author: Landwehr KR, Hillas J, Mead-Hunter R, O'Leary RA, Kicic A, Mullins BJ, Larcombe AN, AusRECTelethon Kids Institute, Centre for Health Research , The University of Western Australia , Nedlands , Western Australia 6009 , Australia.Priority Research Centre for Asthma and Respiratory Disease , Hunter Medical Research Institute , Newcastle , New South Wales 2305 , Australia.Robinson Research Institute , University of Adelaide , North Adelaide , South Australia 5006 , Australia., WAERPOccupation, Environment and Safety, School of Public Health , Curtin University , P.O. Box U1987, Perth , Western Australia 6845 , Australia.. Journal: Environ Sci Technol; 2019 Oct 01; 53(19):11437-11446. PubMed ID: 31453689. Abstract: As global biodiesel production increases, there are concerns over the potential health impact of exposure to the exhaust, particularly in regard to young children who are at high risk because of their continuing lung development. Using human airway epithelial cells obtained from young children, we compared the effects of exposure to exhaust generated by a diesel engine with Euro V/VI emission controls running on conventional diesel (ultra-low-sulfur mineral diesel, ULSD), soy biodiesel (B100), or a 20% blend of soy biodiesel with diesel (B20). The exhaust output of biodiesel was found to contain significantly more respiratory irritants, including NOx, CO, and CO2, and a larger overall particle mass. Exposure to biodiesel exhaust resulted in significantly greater cell death and a greater release of immune mediators compared to both air controls and ULSD exhaust. These results have concerning implications for potential global health impacts, particularly for the pediatric population.[Abstract] [Full Text] [Related] [New Search]