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  • Title: Dual amplification ratiometric biosensor based on a DNA tetrahedron nanostructure and hybridization chain reaction for the ultrasensitive detection of microRNA-133a.
    Author: Zhu L, Ye J, Wang S, Yan M, Zhu Q, Huang J, Yang X.
    Journal: Chem Commun (Camb); 2019 Sep 24; 55(77):11551-11554. PubMed ID: 31490470.
    Abstract:
    A novel ratiometric electrochemiluminescence (ECL)-electrochemical (EC) hybrid biosensor with a high accuracy and reproducibility was fabricated for the ultrasensitive detection of miRNA-133a. With the help of a DNA tetrahedron nanostructure and hybridization chain reaction dual amplification strategy, the detection limit of 12.17 aM for miRNA-133a was obtained.
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