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  • Title: Coincidence of gonadal dysgenesis and hyperprolactinemia.
    Author: Rudolf K, Kunkel S.
    Journal: Exp Clin Endocrinol; 1988 Mar; 92(3):363-5. PubMed ID: 3150957.
    Abstract:
    It is reported about 4 female patients aged from 3 to 31 years (average age 18 years) with gonadal dysgenesis and hyperprolactinemia. Beside one all these females were not treated with synthetic sexual steroids. In 3 of the 4 patients both hyperprolactinemic and hypergonadotropic serum levels were observed. In one case the gonadotropic serum levels were normal. A stimulation test with GnRH-TRH or arginine-GnRH-TRH, respectively, was performed. In patients with gonadal dysgenesis a change on the area of hypothalamo-hypophyseal axis is supposed to cause the hyperprolactinemia.
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