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Title: Reduction in morphological sickling of red cells incubated with quinine. Author: Mankad VN, Moore RB. Journal: Pediatr Hematol Oncol; 1987; 4(1):73-6. PubMed ID: 3152915. Abstract: Quinine HCl reduced the formation of reversibly sickled cells in vitro over a concentration range of 0.2-5.0 mM. Quinidine and chloroquine had similar effects. Combinations of quinine and cyanate demonstrated synergistic, antisickling properties in vitro.[Abstract] [Full Text] [Related] [New Search]