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  • Title: Hemophagocytic syndrome with restricted organ involvement: excessive hemosiderosis and fibrosis of the spleen.
    Author: Zoubek A, Haas OA, Ladenstein R, Gadner H, Radaszkiewicz T.
    Journal: Pediatr Hematol Oncol; 1986; 3(2):135-42. PubMed ID: 3153223.
    Abstract:
    We report the case history of a 6 1/2-month-old girl with a hemophagocytic syndrome, pancytopenia, and excessive hepatosplenomegaly. Some extraordinary histological features present in this case--restricted organ involvement, excessive hemosiderosis, and fibrosis of the spleen--further contributed to the well-known problem of distinguishing between infection-associated hemophagocytic syndrome and familial hemophagocytic lymphohistiocytosis.
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