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  • Title: A Case of Sulfhemoglobinemia Secondary to a Urinary Tract Infection.
    Author: Campagna G, Espaillat A, Pfeiffer T, Powers JM, McClure M, Hess LM.
    Journal: J Pediatr Hematol Oncol; 2020 Nov; 42(8):e765-e767. PubMed ID: 31568176.
    Abstract:
    Sulfhemoglobinemia (SulfHb) is a rare dyshemoglobinemia that can present with cyanosis in the absence of respiratory distress. It has been reported secondary to drug ingestion and chronic constipation. We present a case of SulfHb in an adolescent female with spina bifida and neurogenic bladder in the setting of an Escherichia coli urinary tract infection. An arterial blood gas differentiated a dyshemoglobinemia from other causes of hypoxemia. The resolution was achieved with antibiotics and red cell transfusion. Here we review the pathophysiology of SulfHb and contribute a unique case report to the limited body of literature on this topic.
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