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  • Title: [Common migraine. Changes in conjugated and unconjugated catecholamines].
    Author: Pradalier A, Launay JM, Dry J, Dreux C, Artigou C.
    Journal: Presse Med; 1985 Mar 09; 14(10):583-5. PubMed ID: 3157937.
    Abstract:
    Plasma levels of conjugated and unconjugated catecholamines were measured in 27 migraineurs between attacks, in 9 migraineurs 1 to 2 hours after the onset of an attack, and in 30 controls. There were no significant changes in conjugated catecholamines; in contrast, a significant rise (p less than 0.01; KS test) in unconjugated dopamine, noradrenaline and adrenaline levels was observed during attacks. These results confirm that migrainous attacks are associated with platelet activation and with overactivity of the sympathetic system.
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