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  • Title: Presence and survival of African swine fever virus in leeches.
    Author: Karalyan Z, Avetisyan A, Avagyan H, Ghazaryan H, Vardanyan T, Manukyan A, Semerjyan A, Voskanyan H.
    Journal: Vet Microbiol; 2019 Oct; 237():108421. PubMed ID: 31585648.
    Abstract:
    This research is focused on the study of African swine fever virus (ASFV) survival in the leech Hirudo medicinalis. To detect the infection route of the virus in leeches, two introduction methods were used: blood-feeding from infected swine hosts and exposure to ASFV-contaminated water (leeches cultivated with ASFV). This study found that the survival of ASFV in leeches was much longer than that in leech-free medium. The persistent presence of the virus in leeches and leech excretion was detected in both groups. The virus excreted from both groups of leeches in the terminal stages of the experiment was able to induce productive infection in porcine alveolar macrophages. In an attempt to understand ASFV, transmission to pigs was conducted through the ingestion of leech-cultivated water and leeches that had fed on ASFV-infected animals or that were cultivated environmentally with the virus. The ingestion of some samples at 60-80 days after cultivation demonstrated successful ASFV transmission via per os infection. In conclusion, leeches can serve as a possible reservoirs for ASFV in the absence of its main hosts - pigs and some ticks of the genus Ornithodoros.
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