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  • Title: Severe Leukemoid Reaction in a Case of Soft Tissue Sarcoma: A Case Report.
    Author: Xing Z, Scott B.
    Journal: JBJS Case Connect; 2019 Dec; 9(4):e0368. PubMed ID: 31592819.
    Abstract:
    CASE: A 62-year-old woman presented with severe leukocytosis and systemic symptoms including fatigue, low appetite, and weight loss. After 4 months of evaluation by doctors with extensive laboratory tests and imaging studies, a soft tissue sarcoma in the left posterior distal thigh was revealed. Quickly after surgical excision of the soft tissue sarcoma, the leukocytosis and systemic symptoms were dramatically resolved. CONCLUSIONS: Leukemoid reaction can present as a paraneoplastic syndrome. Awareness of soft tissue sarcoma as a possible cause of leukemoid reaction may help improve the early diagnosis and subsequent early intervention in future cases.
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