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  • Title: A NIR-emitting cyanine with large Stokes shifts for live cell imaging: large impact of the phenol group on emission.
    Author: Dahal D, McDonald L, Pokhrel S, Paruchuri S, Konopka M, Pang Y.
    Journal: Chem Commun (Camb); 2019 Oct 31; 55(88):13223-13226. PubMed ID: 31595909.
    Abstract:
    There are a limited number of near-infrared (NIR) emitting (λem = 700-900 nm) molecular probes for imaging applications. A NIR-emitting probe that exhibits emission at ∼800 nm with a large Stokes shift was synthesized and found to exhibit excellent selectivity towards mitochondria for live-cell imaging. The photophysical properties were attributed to an excited "cyanine structure" via intramolecular charge transfer (ICT) involving a phenol group.
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