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  • Title: CSF beta-endorphin and beta-lipotropin in Alzheimer's disease and multi-infarct dementia.
    Author: Sulkava R, Erkinjuntti T, Laatikainen T.
    Journal: Neurology; 1985 Jul; 35(7):1057-8. PubMed ID: 3159972.
    Abstract:
    We measured CSF levels of the opioid peptides beta-endorphin and beta-lipotropin in patients with Alzheimer's disease, multi-infarct dementia and controls. In both dementia groups, the mean concentration of beta-endorphin was significantly lower than in controls. The mean beta-lipotropin levels did not differ significantly in the two groups. The low CSF beta-endorphin level may relate generally to dementia.
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