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  • Title: Modulation of T-cell subsets in asthmatic children by THF, a thymic hormone.
    Author: Shohat B, Volovitz B, Varsano I, Trainin N.
    Journal: Ann Allergy; 1985 Jul; 55(1):52-6. PubMed ID: 3160267.
    Abstract:
    Induction of theophylline-sensitive T-suppressor cells with THF, a thymic hormone, resulted in elevation of the low levels of these lymphocytes in non-treated asthmatic children. Evaluation, however, by monoclonal OKT8 antibodies did not show changes in the levels of the OKT8+ cells after THF incubation. In the treated asthmatic children, normal levels of theophylline-sensitive T-suppressor cells as well as OKT8+ cells were found. These normal levels were not changed with THF after in vitro incubation.
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