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Title: Induced cultivation pattern enhanced the phycoerythrin production in red alga Porphyridium purpureum. Author: Xu Y, Jiao K, Zhong H, Wu S, Ho SH, Zeng X, Li J, Tang X, Sun Y, Lin L. Journal: Bioprocess Biosyst Eng; 2020 Feb; 43(2):347-355. PubMed ID: 31606754. Abstract: Porphyridium purpureum is a rich source for producing phycoerythrin (PE); however, the PE content is greatly affected by culture conditions. Researchers have aimed to optimize the cultivation of P. purpureum for accumulation of PE. When traditional optimized culture conditions were used to cultivate P. purpureum, high PE contents were not usually achieved. In this study, an induced cultivation pattern was applied to P. purpureum for PE biosynthesis (i.e., an incremental approach by altering temperatures, light intensities, and nitrate concentrations). Results revealed that the induced pattern greatly improved the PE biosynthesis. The optimized PE content of 229 mg/L was achieved on the 12th cultivation day, which was a maximum PE content within one cultivation period and accounted for approximately 3.05% of the dry biomass. The induced cultivation pattern was highly suitable for PE synthesis in P. purpureum, which provided an important reference value to the large-scale production of PE.[Abstract] [Full Text] [Related] [New Search]