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  • Title: Radiation-induced osteosarcoma of the skull mimicking cutaneous tumor after treatment for frontal glioma.
    Author: Maruyama A, Yasuoka S, Katoh N, Asai J.
    Journal: J Dermatol; 2020 Jan; 47(1):69-71. PubMed ID: 31637750.
    Abstract:
    Radiation-induced sarcomas are recognized complications of radiation therapy and are associated with poor prognosis. Radiation-induced osteosarcoma is one of the rare types of radiation-induced sarcomas, with the risk of radiation-induced osteosarcomas being only 0.01%-0.03% among all patients treated with radiotherapy. There have been only four reported cases of radiation-induced osteosarcomas after radiotherapy for gliomas. Here, we report a unique case of radiation-induced osteosarcomas arising on the skull and extending to the skin, with a short latent period. We also review the clinical features of the previously reported cases.
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