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  • Title: The 'Finnish new variant of Chlamydia trachomatis' escaping detection in the Aptima Combo 2 assay is widespread across Norway, June to August 2019.
    Author: Johansen TB, Kløvstad H, Rykkvin R, Herrfurth-Erichsen EB, Sorthe J, Njølstad G, Ebbesen MH, Nygaard RM, Sandmoen EK, Thilesen C, Onken A, Liljedal I, Hadad R, Unemo M.
    Journal: Euro Surveill; 2019 Oct; 24(42):. PubMed ID: 31640843.
    Abstract:
    The 'Finnish new variant of Chlamydia trachomatis' (FI-nvCT), escaping detection in the Aptima Combo 2 assay (AC2), is widespread across Norway. From June to August 2019, 84% (81/97) of available AC2/Aptima CT discordant samples from five laboratories were confirmed as FI-nvCT. Two additional CT variants (CT 23S rRNA C1514T and G1523A) also escaped AC2 detection. The high FI-nvCT proportion might indicate a long-term national spread and it cannot be excluded that FI-nvCT emerged in Norway.
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