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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Submucous fibrosis in non-betel nut chewing subjects.
    Author: Seedat HA, van Wyk CW.
    Journal: J Biol Buccale; 1988 Mar; 16(1):3-6. PubMed ID: 3165090.
    Abstract:
    Six patients with the typical features of submucous fibrosis (SF) but without a history of betel nut chewing or an abnormal intake of chillies are described. All had palpable fibrous bands in their mouths and limited mouth opening as well as a variety of symptoms associated with SF. Biopsy specimens of the cheeks showed the classic features of SF, an atrophic epithelium and a very dense lamina propria. Also seen were hyperkeratosis, atypia and signet cell-like degeneration of the epithelium and chronic inflammation of the lamina propria. In 3 cases the fibrosis extended into the submucosa. As no reason for the disease could be demonstrated the question is asked whether people with a genetic predisposition can develop SF spontaneously.
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