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  • Title: Whole genome analysis of Black Bengal goat from Savar Goat Farm, Bangladesh.
    Author: Chowdhury SMZH, Nazir KHMNH, Hasan S, Kabir A, Mahmud MM, Robbani M, Tabassum T, Afroze T, Rahman A, Islam MR, Hossain M.
    Journal: BMC Res Notes; 2019 Oct 24; 12(1):687. PubMed ID: 31651366.
    Abstract:
    OBJECTIVES: Single nucleotide polymorphisms (SNPs) play critical roles in genetic diversity and disease. Many traits and diseases are linked with exonic SNPs that are significant for gene function, regulation or translation. This study focuses on SNPs that potentially act as the genetic basis for desirable traits in the Black Bengal Goat. This variety of goat is native to South Asia, and is identified as one of the most commercially important meat producing animals in the world. The aim of this study was to sequence the genome of Black Bengal Goats and identify SNPs that might play a significant role in determining meat quality in the organism. The study focuses on exonic SNPs for their greater likelihood of affecting the final translated protein product. RESULTS: Approximately 76,000 exonic variants were identified in the study. After filtration using a Wilcoxon test based score, the number came down to 49, 965 which were found to be distributed in 11,568 genes. The functional pathways affected by these variations included fatty acid metabolism and degradation, which are important processes that influence meat quality.
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