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  • Title: Perforation of the intestine in inflammatory bowel disease. An OMGE survey.
    Author: Softley A, Clamp SE, Bouchier IA, Myren J, Watkinson G, de Dombal FT.
    Journal: Scand J Gastroenterol Suppl; 1988; 144():24-6. PubMed ID: 3165552.
    Abstract:
    This presentation assesses the incidence of perforation of the intestine in patients with inflammatory bowel disease by reviewing the incidence of this complication in a total of 3175 patients from the OMGE inflammatory bowel disease multi-national survey. Amongst 1928 patients with ulcerative colitis, perforation was noted in only 5 (0.3%), which is much lower than in previous series (from 1% to 2%). By contrast, 19 of 1247 patients with Crohn's disease had perforated (1.5%). The survey thus suggests that the incidence of perforation in ulcerative colitis has fallen in the last 2 decades, probably as a result of the widespread implementation of early surgery. The risk of perforation of Crohn's disease remains quite high.
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