These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Interaction of amino acyl-tRNA-synthetases from the rabbit liver with RNA and polyanions].
    Author: Vol'fson AD, Motorin IuA, Tsygankov AIu, Orlovskiĭ AF, Gladilin KL.
    Journal: Biokhimiia; 1988 May; 53(5):799-805. PubMed ID: 3167123.
    Abstract:
    The interaction of aminoacyl-tRNA synthetase with RNA and polyanions was studied. The inhibition of the enzymes by polyU, polyI and heparin was demonstrated. It was found that this interaction is of limited specificity and is typical of single-stranded RNAs which possess no orderly secondary structure as well as of other polyanions possessing similar polyelectrolytic properties. Data from kinetic analysis and lysyl-tRNA synthetase modification by pyridoxal phosphate are suggestive of participation of the tRNA binding site in the enzyme interaction with polyanions.
    [Abstract] [Full Text] [Related] [New Search]