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Title: Peroxidase-like Activity of Metal-Organic Framework [Cu(PDA)(DMF)] and Its Application for Colorimetric Detection of Dopamine. Author: Wang J, Hu Y, Zhou Q, Hu L, Fu W, Wang Y. Journal: ACS Appl Mater Interfaces; 2019 Nov 27; 11(47):44466-44473. PubMed ID: 31691561. Abstract: A metal-organic framework (MOF) [Cu(PDA)(DMF)] was synthesized under mild mixed solvothermal conditions. It is constructed by 1,10-phenanthroline-2,9-dicarboxylic acid (H2PDA) and Cu2+ ions. The complex exhibits high peroxidase-like activity and can catalytically oxidize the colorless substrate 3,3',5,5'-tetramethylbenzidine to a blue product in the presence of H2O2. However, the peroxidase-like activity of [Cu(PDA)(DMF)] can be potently inhibited in the presence of dopamine. Based on this phenomenon, the colorimetric detection of dopamine was demonstrated with good selectivity and high sensitivity. [Cu(PDA)(DMF)] showed good stability and robust catalytic activity, which has been employed in the detection of dopamine in human urine and pharmaceutical samples.[Abstract] [Full Text] [Related] [New Search]