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  • Title: Epidemiological aspects of intraocular pressure in an onchocerciasis endemic area.
    Author: Thylefors B, Duppenthaler JL.
    Journal: Bull World Health Organ; 1979; 57(6):963-9. PubMed ID: 317024.
    Abstract:
    A field investigation of intraocular pressure in populations in onchocerciasis endemic areas of West Africa revealed a normal pressure distribution in individuals without signs of ocular onchocerciasis or with only microfilariae or reversible lesions in the eye. Females showed a significantly higher mean ocular tension, and in both sexes tension decreased with age. Patients with irreversible onchocercal ocular lesions and signs of anterior uveitis showed a significantly lower and abnormally distributed intraocular pressure. The prevalence of glaucoma was significantly higher in this group, thus indicating that a high intensity of onchocercal infection may be associated with a risk of secondary glaucoma. The presence of microfilariae in the ocular tissues and consequent inflammatory reactions may possibly give rise to an abnormal distribution of ocular tension.
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