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  • Title: Prognostic significance of cell surface markers in childhood acute lymphoblastic leukaemia.
    Author: Kumar S, Carr TF, Evans DI, Morris-Jones P, Hann IM.
    Journal: Clin Lab Haematol; 1979; 1(2):121-8. PubMed ID: 317037.
    Abstract:
    Examination of surface markers on leukaemic blasts from 51 children with ALL revealed that ALL is a heterogeneous disease. The majority (68%) of patients with ALL lack surface markers (null leukaemia); 28% could be classed as T cell as they form rosettes with sheep RBC and 4% have been shown to possess surface immunoglobulins and hence are classed as B cells. The children with null cell leukaemia have a better prognosis than T and B cell types.
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