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  • Title: Altered glycosylation is induced in both alpha- and beta-subunits of human chorionic gonadotropin produced by choriocarcinoma.
    Author: Endo T, Nishimura R, Mochizuki M, Kochibe N, Kobata A.
    Journal: J Biochem; 1988 Jun; 103(6):1035-8. PubMed ID: 3170515.
    Abstract:
    The two subunits of human chorionic gonadotropin (hCG) purified from the urine of a patient with choriocarcinoma were successfully separated by SDS-polyacrylamide gel electrophoresis. A comparative study of the oligosaccharides released from the two subunits by hydrazinolysis revealed that altered glycosylation occurs in both subunits and possibly at all four asparagine sites of the choriocarcinoma hCG molecule.
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