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  • Title: [Analysis of a model of the miniature endplate current].
    Author: Nigmatullin NR, Snetkov VA, Nikol'skiĭ EE, Magazanik LG.
    Journal: Neirofiziologiia; 1988; 20(3):390-8. PubMed ID: 3173582.
    Abstract:
    The numerical model of the miniature end-plate current MEPC described earlier was systematically analyzed to obtain an optimal set of parameters. This set permits simulating a number of experimental effects: time course of normal MEPC, cholinesterase inhibition, alpha-bungarotoxin action, potential dependence of MEPC, etc. The time course of the simulated "giant" MEPC fitted the experimental data only partially. A good correspondence between the model and experimental data underlies the conclusion that this model reflects well the relative contribution of several processes to MEPC generation.
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