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  • Title: [Gadolinium DTPA in a MR study of expansive lesions of the cranial base].
    Author: Bartolozzi C, Olmastroni M, Dal Pozzo G, Petacchi D.
    Journal: Radiol Med; 1988 Sep; 76(3):152-7. PubMed ID: 3175068.
    Abstract:
    Twenty-five patients were investigated by MR imaging in order to evaluate the diagnostic value of Gadolinium (Gd)-DTPA in skull-base tumors. The patients were studied with standard acquisition techniques (T1, mixed and T2-weighted images) without contrast medium. The images obtained were then compared with the T1-weighted images obtained after intravenous injection of Gd-DTPA. The contrastographic results in the different types of acquisition were evaluated. Thanks to the extraordinary increase in contrast resolution it provides, Gd-DTPA allowed the precise evaluation of the lesion and of its perfect spatial definition in all cases. Our experience demonstrated that Gd-DTPA considerably increases the sensitivity of the technique in this anatomical region. On the contrary, as regards the nature of the lesion, the signal did not significantly vary after the iv injection of Gd-DTPA in the various kinds of lesion. In addition to the important diagnostic advantages of Gd-DTPA, its excellent tolerability and the absence of side-effects must be stressed.
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