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  • Title: Circumscribed lytic lesions of the thalassaemic skull.
    Author: Orzincolo C, Castaldi G, Bariani L, Franceschini F, Corcione S, Scutellari PN.
    Journal: Skeletal Radiol; 1988; 17(5):344-7. PubMed ID: 3175693.
    Abstract:
    Solitary or multiple circumscribed osteolytic areas are described in seven patients, selected from 250 patients with homozygous beta-thalassaemia (Cooley's anaemia). On X-ray examinations, these areas appear as purely osteolytic lesions with well-defined margins not associated with sclerosis. The possible mechanisms are discussed.
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