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  • Title: Assignment of gene for coagulation factor V to chromosome 1 in man and to chromosome 13 in rat.
    Author: Dahlbäck B, Hansson C, Islam MQ, Szpirer J, Szpirer C, Lundwall A, Levan G.
    Journal: Somat Cell Mol Genet; 1988 Sep; 14(5):509-14. PubMed ID: 3175767.
    Abstract:
    Two different factor V cDNA fragments were used as hydridization probes in the chromosomal assignment of the human and rat factor V genes. A 1.6-kb EcoRI fragment was used as a hybridization probe to analyze a panel of human-rodent somatic cell hybrids. Cosegregation of factor V specific DNA restriction fragments with human chromosome 1 was observed. In addition, a panel of rat-mouse somatic cell hybrids was analyzed with another human factor V cDNA probe to localize the gene for rat coagulation factor V. In the rat, the gene for coagulation factor V was found to be located in chromosome 13. This is the first gene in the rat to be localized to chromosome 13.
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