These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Obstructive nephropathy; kidney function and renal excretion of prostaglandin (E)2 and Thromboxane B(2) following percutaneous decompression nephropyelostomy].
    Author: Weber T, Sauer A, Brühl P, Kramer HJ.
    Journal: Urologe A; 1988 Sep; 27(5):269-74. PubMed ID: 3176214.
    Abstract:
    In patients with chronic urinary obstruction the excretion of prostaglandin E(2) (PGE2) and thromboxane B(2) (TXB2) was measured. During obstruction signs of an increased vasoconstrictor (TXB2)- and a decreased vasodilator (PGE2) activity were found. After percutaneous nephropyelostomy a reverse pattern with decrease of the initially high (TXB2) excretion and increase of the PGE(2)excretion was observed. It is suggested that these changes of the arachidonic acid metabolism previously found in animals also take part in the pathophysiological changes in humans after relief of urinary obstruction having significant effect of renal blood flow, glomerular filtration rate and tubular function in obstructive nephropathy in humans.
    [Abstract] [Full Text] [Related] [New Search]