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  • Title: The effect of truncal vagotomy on the bicarbonate-ion secretion of the stomach in rat.
    Author: Dubecz S, Szombath D, Sándor J, Gáti T.
    Journal: Acta Chir Hung; 1988; 29(2):131-6. PubMed ID: 3176787.
    Abstract:
    The effect of truncal vagotomy on the gastric bicarbonate-ion, H-ion and chloride-ion secretions of the rat was studied experimentally. In the first half hour after truncal vagotomy, besides the known decrease of the H-ion, also the bicarbonate-ion and chloride-ion secretions were found reduced. The decrease in bicarbonate ion secretion was smaller as compared to the H-ion secretion. After two hours, there was no difference in bicarbonate-ion and chloride-ion secretions as compared to the controls and to the vagotomized groups. According to their results, following truncal vagotomy applied in the surgical management of ulcer, the bicarbonate-ion secretion of the stomach decreases immediately after operation. This decrease is, however, only transitory the bicarbonate-ion secretion becoming normal within a short time.
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