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  • Title: [Therapeutic results in Giardia lamblia infestation].
    Author: Martínez Costa C, García Vila A, Brines Solanes J, Codoñer Franch P.
    Journal: An Esp Pediatr; 1988 May; 28(5):425-8. PubMed ID: 3178058.
    Abstract:
    Therapeutic effects of metronidazole (Flagyl), tinidazole (Tricolam 500) and chlorhydrate of quinacrine in a study of 106 children with symptomatic giardiasis are compared. To evaluate results, cure percentage, efficacy and presence of secondary effects were quantified. Tinidazole was demonstrated most effective drug (96% effective) when compared with quinacrine (83.3% effective) and metronidazole (70.2%) (p less than 0.05). Authors recommend following regime: tinidazole 50-75 mg/kg divided in 2-3 doses, one day; chlorhydrate of quinacrine 6 mg/kg/day divided in 3 doses, five days; metronidazole 15-20 mg/kg/day divided in 3 doses, seven to ten days.
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