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  • Title: Dental effects of Lycasin in the diet of laboratory rats.
    Author: Grenby TH.
    Journal: Caries Res; 1988; 22(5):288-96. PubMed ID: 3180160.
    Abstract:
    Lycasin was included in diets fed to caries-active Osborne-Mendel rats for periods up to 8 weeks. The animals could tolerate up to 15-16% of Lycasin in dry-powder diets and up to 25% in pelleted diets before gastro-intestinal disturbance. Lycasin 80/55 at 25% in the diet was non-cariogenic, producing a very low level of caries, similar to that on a maize starch regimen and significantly below that on a sucrose regimen. At 16% in the diet D-sorbitol was even less cariogenic than Lycasin. Compared with the sucrose control, the reductions in caries scores were 89% on the sorbitol and 72% on the Lycasin 80/55 regimen.
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