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  • Title: Utility of 24 hour bone scan in evaluation of bone involvement by soft tissue sarcoma.
    Author: Mekhmandarov S, Azaria M, Engelberg S, Lieberman LM.
    Journal: Clin Nucl Med; 1988 Sep; 13(9):649-51. PubMed ID: 3180612.
    Abstract:
    Accumulation of Tc-99m MDP in soft tissue malignancies occurs frequently. When tumor overlaps adjacent bone structures, the bone margins can be indiscernible on a regular bone scan. Additional views should be taken to differentiate bone from tumor, however, separation is sometimes difficult and not always successful. This report presents a patient in whom accumulation of Tc-99m MDP in a liposarcoma of the thigh disappeared on a 24 hour scan and bone margins were seen clearly. A possible mechanism for this phenomenon and its utility are discussed.
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