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  • Title: Changes of contact phase proteins during haemodialysis.
    Author: Vicente V, Alegre A, Alberca I, Lopez Borrasca A, Gomez JR, Macias JF.
    Journal: Haematologia (Budap); 1988; 21(3):159-62. PubMed ID: 3181818.
    Abstract:
    Functional and immunological activities of factors XII and XI, Prekallikrein, high molecular weight kininogen and C-1-esterase inhibitor were studied in eight patients before, during and after haemodialysis. During and after dialysis sessions a significant decrease in the functional activities of Prekallikrein and high molecular weight kininogen (p less than 0.05) could be detected, whereas their immunological levels did not change. Furthermore C-1-esterase inhibitor increased after dialysis (p less than 0.05). These results indicate activation of the kinin system during haemodialysis.
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