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Title: Fragilides U-W: New 11,20-Epoxybriaranes from the Sea Whip Gorgonian Coral Junceella fragilis. Author: Su TP, Yuan CH, Jhu YM, Peng BR, Wen ZH, Wu YJ, Wu TY, Liu HW, Sung PJ. Journal: Mar Drugs; 2019 Dec 15; 17(12):. PubMed ID: 31847481. Abstract: Three new 11,20-epoxybriaranes-fragilides U-W (1-3), as well as two known metabolites, junceellonoid D (4) and junceellin (5), were obtained from the octocoral Junceella fragilis. The structures of briaranes 1-3 were elucidated by spectroscopic methods and briaranes 3 and 5 displayed inhibition effects on inducible nitric oxide synthase (iNOS) release from RAW264.7.[Abstract] [Full Text] [Related] [New Search]