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  • Title: A technique to study splanchnic metabolism in the unrestrained conscious pig.
    Author: van Berlo CL, van den Bogaard AE, Bost MC, Soeters PB.
    Journal: Lab Anim Sci; 1988 Aug; 38(4):463-6. PubMed ID: 3184858.
    Abstract:
    In recent years similarities recognized between porcine and human anatomy and physiology have made the pig an experimental animal of considerable value in biomedical research. We developed a pig model for unrestrained repeated sampling of portal and arterial blood, and selectively of small and large bowel veins. Catheters were inserted, under halothane anesthesia, in ten female crossbred (Yorkshire x Dutch Landrace) piglets (8 weeks; 20 +/- 2 kg). After recovery for at least 3 days the catheters were used for sampling of blood. Aortic and portal catheters patency rates were 60% at day 24. For the small bowel catheters, a patency rate of 30% was seen at day 24. The large bowel patency rate was 30% at day 10. These results are promising because they allow long-term metabolic splanchnic research in unrestrained piglets.
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