These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Changes of serum interleukin-6 in healthy pregnant women and establishment of relevant reference intervals.
    Author: Fu Y, Tang L, Hu M, Xiang Z, Hu Y.
    Journal: Clin Chim Acta; 2020 Mar; 502():116-119. PubMed ID: 31866334.
    Abstract:
    OBJECTIVE: To explore the changes of serum interleukin-6 (IL-6) levels in healthy pregnant women and establish reference intervals (RIs). METHOD: According to the requirements for the RIs study model and the reference population screening criteria in C28-A3 document, Serum IL-6 levels were measured by electrochemiluminescence immunoassay in 480 healthy Chinese women, including 120 pregnant women in each of the first, second and third trimester and 120 non-pregnant women as the negative control. The establishment of RIs for IL-6 were defined using nonparametric percentile. RESULTS: The RIs for serum IL-6 levels in healthy pregnant women is <4.19 pg/ml, the RIs for serum IL-6 levels in healthy pregnant women who are in the first trimester is <3.52 pg/ml, and the RIs for serum IL-6 levels in healthy pregnant women who are in the second and third trimester is <4.40 pg/ml. CONCLUSIONS: Serum IL-6 level in healthy pregnant women is higher than the healthy non-pregnant women, and the level of IL-6 who are in the second and third trimester is higher than those in the first. This paper successfully established RIs for serum IL-6 levels in pregnant women, providing a reference for clinical medical staff and laboratory workers.
    [Abstract] [Full Text] [Related] [New Search]